A talented guy in Sterling, Alaska built a 450 #2 nitro on a 12g CZ/Huglu. Did a dandy job. The action was off face when he showed me the gun. The very large diameter of this case provided more back thrust than the CZ could handle. He might have been somewhat better off with the standard 450 nitro. My 450 nitro on a pre WW1 J.P.Sauer is holding up just fine.

Otto