Looking good. My .458 2" made 2,296fps with Hornady RN's and they really did well on our moose. Years ago, I posted a picture here of a (675lb.in quarters) bull I shot with this load and rifle. Of course, that was a Mauser Bolt action and close to top-end loads. I used the same loads with 350gr. Horn., 400gr. Barnes Spitzers and 500gr. Hornady RNs. The velocities ran 2,296fps, 2,159fps and 2,059fps.

I suspect your .45 2.4" should do likewise, if you are getting close to 2,300fps with 350's.
I used 68.0gr. H335 and 66.0gr. IMR4320. These were compressed loads.
The H335 made quite the fireballs fired at night.
I suspect I could have done the same or similar with H4895.
Too, my rifle had 3/8" freebore and allowed seating the bullets well out of the case, so would be similar to a short throated .45 2.3", I guess.