Those look horrible.

Pedersoli has the cartridge SxS handgun in 45 Colt / 410 shotshell.

https://www.davide-pedersoli.com/scheda-...oli-howdah.html

This chamber is a great opportunity to use different brass and Colt diameter bullets with huge powder loads if you dare.

I've had over 60 grains 3031 and 300 grain bullets in a similar chamber, but in a much lighter single barreled handgun.
That's right up there in "stomp the shit out of them" performance.