Dono - that's a good sounding load. At that speed, that bullet should give good penetration and expansion. I'd think it would be a smasher for 'Donks' or any ungulates here. 2207? - is that Varget?

In a 2.4" or 2.6" case, I'd think a speed in the 2,000fps to 2,050fps range (bit more with a longer case) would be possible, same pressure range.

The slower powders will deliver at lower pressure. Just make certain there is enough pressure to get a good burn and not coat the bore with unburnt powder - some do. In these straight sided cases, the ball powders don't work well until you get the pressures well up past most DR ranges.