Thank you all. I reload for all my rifles so I would expect to precisely prepare a set of loads for the regulation process. I know that the range of game I listed is too great for this rifle and any particular load. If I knew exactly what I was going to hunt with this gun it would be a lot easier for you and me but I don't. I have several pre-64 Mod. 70s in my gun safe that I have used for years. I have a ranch in north central Montana so have mule and whitetail deer in my back yard. My preferred rifle for them is a pre-64 Win. Mod. 70 in .264 Win. Mag. I am CNC milling this Winchester 21 receiver for the 45-70 from a solid block of chrome moly 4340 steel and will appropriately harden it. It will be much stronger that the original 21s who were alrealy plenty strong. I am also making a titanium 21 20ga shotgun at the same time as a companion to the DR. It is a project of love since I have a lot of firepower already. I just don't know exactly what I will use it for yet; I wish I did! It seems that we may be converging on a 350 grain Hornady as an all around bullet. I had hoped to push it beyond 2000 ft/sec but I don't know if that is safe or practical. I really need your considered opinion on this.

Thank you all for the input and further help.---Bill