Absolutely true.

Scopes are like women though, everybody has their preferences.

If for some reason you want a higher power, go for it. My .375 wears the same M8-4X Leupold I stuck on it when I bought the rifle in 1987 or so. I have made do and for most hunting it has been fine; plains game in southern Africa and deer and elk here.

But a good 3x9 would be a great option for a .375 as well. In fact, over the years I have used the upper powers of my variables on other rifles quite a bit, particularly for shooting from one of my stands or "Blitz Blinds" and I am watching a deer move thru the timber edge and I want to make sure I do not nick a branch when I shoot.

All that to say it totally depends on the game you intend to hunt and where you intend to hunt it.

When I bought my first .375 years ago, I put a 2 1/2x Leupold on that rifle based on some of the common gun writer recommendations of the time. Those worthies continually mantra'd that a ".375 doesn't need magnification". Then I came to realize that the CALIBER doesn't matter, the GAME and COUNTRY do. And for my hunting of deer, elk and African plains game, more magnification has come in handy very often. That 2 1/2x would have been a mistake many times over had I kept that rifle and scope for long. As it is, the 4x has served me pretty well.

Orient your choice around the game and country you intend to hunt and you will do fine.