My vote too is for the 375 H&H. There are many, many choices to have fun with, but that velvet-smooth feeding, easy-to-load, no-hassle, find-ammo EVERYWHERE, resell-if needed, cheap-to-shoot for a biggy, flat-shooting, hard-hitting, with-character, wide-bullets-choice, is the 375 H&H. You an specialize in any direction for many reasons. But have the one you can always go to when you HAVE to hunt anything, anywhere. You will probably find ammo in some little gas station in the middle of anywhere in 375 H&H, maybe not in all the rest. Then have fun w/ something more exotic when you can.