I don’t have rifles in any of the calibers mentioned, a .30-338 Win Mag is my largest, that said I have great personal interest in the DG calibers.

I’ve thought, after many ballistics, trajectory, and case dimension/capacity comparisons that there was something to said about the usefulness of .30, .33, .35, and .40 Newton cartridges (I understand that neither Newton nor the originator Adolph designed the .40 Newton). The .30 and .40 Newton cartridges chambered in modern SS rifles would hunt anywhere.

That said, I’ve been fanaticizing on either a .416-375 Ruger or a .423-375 Ruger wildcat cartridge as my big bore load with either a .300-375 Ruger or a .338-375 Ruger wildcat cartridge as my medium bore load as the .375 Ruger case is somewhat readily available (though mostly sold out) while the Newton cases are almost impossible to find.

The Chuck Hawks website has some interesting information that may assist in your personal decisions – here are a few hyperlinks of the many that I’ve used:

Sectional Density vs. Game Weight:
http://www.chuckhawks.com/subscribers/tables_charts_lists_page/sd_vs_game_weight.htm

Expanded Rifle Ballistics Summary:
http://www.chuckhawks.com/subscribers/tables_charts_lists_page/rifle_ballistics_summary_exp.htm

Expanded Rifle Trajectory Table:
http://www.chuckhawks.com/subscribers/tables_charts_lists_page/rifle_trajectory_table_exp.htm

Expanded Optimal Game Weight Table:
http://www.chuckhawks.com/subscribers/tables_charts_lists_page/game_range_caliber_exp.htm

Expanded and Improved Rifle Ballistics Table:
http://www.chuckhawks.com/subscribers/tables_charts_lists_page/rifle_ballistics_table2_exp.htm

Hope these are of use to you.