...I'll second the choice of .416 caliber. And don't worry about not having enough "ooomph" at over 150yds. In Zambia in '03, I had no option but to shoot a Cookson's wildebeeste at 180yds, and I also shot a Cape buffalo at a smidge over 200yds. Rifle caliber: .416 Taylor with 400gr A-Frame bullets. Both animals: DEAD RIGHT THERE!!

I also own/shoot a .375H&H,and if I were to plan on big bears, I may select the .375H&H. However, for African DG, the H&H stays home, and the 40cal goes to the Dark Continent with me.

Heck, make up one of each.