Nitro, I shot a cow elk a few years at almost 180 yds. as she was turning away to boogie on me. I shot her with my 375 H&H with Speer 285's, 4 down and 1 up. I punched straight through both shoulders and she went down in a heap with her legs splayed out. I worried about the meat damage and saw that like Elmer Keith said years ago, you could eat all the way up to the bullet hole.