I've blown the lungs out of many an antelope (100-125#), with 300 grain Partitions (375 H&H). Damage was dramatically less than that of my friend's 7mm Rem Mag shooting Partitions on antelope.

Hornady 270 soft points out of my H&H left some pretty impressive exit wounds in the antelope.

I believe bullet construction and impact velocity have much more effect upon meat damage than does calibre.

That 7mm mag hits at a much higher velocity than my old H&H does given the same prey range.

So many variables, e.g., homogenous tissue, bone density, animal size, etc., all render the topic quite variable.

Similar to the endless studies involving stopping power in the combat handgun genre.

We do ask much of our projectiles, eh?!