When much younger, I used to revel in getting smacked and controling the big ones. hardest for me was a .505 Barnes Supreme, with 600gr. Solid at 2,800fps. That one spun me around like a weathercock. My .375H&H felt like a triple deuce after that one.
: Currently, the .458 Alaksan with 400gr. at 2,400fps is quite enough, but at 10-1/2 pounds is easier to shoot than my .375/06IMP at 8 pounds with 300's at 2,470fps.
: Nowadays I draw the line at those two.