Hunting situation--

You are stalking a BIG Buff in heavy cover and finally see him standing and then ONLY a front shoulder narrowly and clearly.Brush obscures other shooting placement

Double rifle tactics-Do you shoot your solid first going for crushing the shoulder, sending bone fragments through and through or do you shoot your A Frame soft trying to avoid the shoulder joint??

Big bolt guys? You gonna cycle that action(assume soft, then solids) at combat range or try to shoot and miss the shoulder bones??

I am concerned about a shoulder bullet blowup and then a wounded really Pissed off Buff--

Maybe you should pass on this monster Buff--

Gerntlemen--
What is the best tactics for each type rifle and WHY?.
Whatcha gonna do?

Thanks to all for any opinions on this scenario.