Any of the bullet weights you've mentioned will work well in the 2200-2500 fps range. You will probably discover that penetration in game does not change significantly between light and heavy bullets of the same construction. The reason is that the higher velocity of the lighter bullet makes up for it's smaller mass. Still, I favour heavy for caliber bullets, as I believe their terminal properties are more predictable. Depending upon bullet design, a heavier bullet may also expand to a larger diameter, and thus produce a larger permanent wound cavity. I think that a 300 gr bullet at 2200 would be a hell of a black bear load, and the steeper trajectory should not be an undue hardship in most black bear habitat.