I have taken elk, black bears, a cape buffalo, oryx, eland, bison(s), nilgai, aoudad, zebra, whitetail, and feral hogs with the 45-70. All have been less than 150 yard shots with most under 75 yards. All together about 50 animals. The PUNCH bullets from Grizzly Cartridge has gone through everything. The 405g from Buffalo Bore is too soft for deep penetration. However, the Grizzly 405g Kodiak Bullet is a bonded core that has penetrated very well.
I have taken nearly the same # of animals of the same types with the 450/400's with 400g Woodleigh Weldcore's. The penetration and performance were all similar to the 45-70 Kodiaks.
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