I put a 300 grainer through the ribs of an elk this year with my 375. It was enough gun though my partner was using an 8mm Rem Mag with 200 gr NP and they were a little light in my opinion (for the round; in a 8mm mauser I'm sure they would have been fine). Elk are a hell of a lot tougher than moose or deer so I would not hesitate to take a 416 elk hunting.