From a .405 Win. a 300 gr. bullet at approximately 2,200fps to 2,250fps would make a superb round for all North American game to and including the big bears, as a hunting round.
: I would not consider it for dangerous game, but then, have no experience with it on dangerous game. Similar ballistics, with good bullets, have been touted as being good large cat-rounds. I think the line should be drawn there as far as dangerous game is concerned.
: In North America, it would be terrific to about 200 yds. on ungulates and close-in on the big bears.