About that 220gr. load at 2,000fps. It is no slouch. No flies on those ballistics.
I shot 2 moose with my wife's .375 model 94 BigBore back in the 1980's, with a 220gr. Hornady FP, loaded with lighlty compressed load of 42gr. H335 for a velocity of 1,920fps.
One moose took 2 steps and dropped from a side chest hit. The other, shot at approximately 95 or 100 yards, we found out had his back to us and was looking at us over his back. He dropped at the shot, but got up and limped away. We waited 15 or 20 minutes then took up the trail. There was blood, but only speck here and there in the low scrub's leaves (blue berries). The dew on the leaves was frustrating as it made the leaves that were turning colour (to reds) all look like they were covered with blood. He was throwing his hind legs oddly & that was the main method of tracking him through the small "sallel" sort of leaves. After an hour and 1/2 we finally caught up to him. He turned and tried to run, but a shot from the right rear quarter, angled up through his lungs, dropping him in 2 or 3 steps. Once getting up to him, a shot through the melon finished him. We then found my first shot had hit him perfectly, or would have been, had he been facing us. It broke the hind leg it hit. Imagine that.
Good load. We were lucky in being able to track him so far - probably a mile of more. The bush there is quite open and that made it easier, but oft times I was on my hands and knees, touching wet leaves with a finger to see if it was water or blood.
That's a LOT of verbiage just to say that a .375", 220gr. bullet at 1,900fps to 2,000fps is not a toy. Oh well.
Oh, to be young again. I was in my 30's.