The cartridge 378 Weatherby Magnum is not particularly suitable as a cartridge for big game hunting, but it is, due to its very good external ballistics, very suitable for long-range shooting.

I am very satisfied with the working of the cartridge 340 Weatherby Magnum when it comes to long-range shots on heavier game species, but I would easily exchange it for the cartridge 378 Weatherby Magnum for the same purposes. Unfortunately, most rifles caliber 378 Weatherby Magnum are conceptually intended as rifles for big game hunting, except this one:

https://egun.de/market/item.php?id=19306483

I like it very much, unfortunately due to my age I no longer have a need for such a rifle.