I have shot buffaloes in Africa and southeast Asia with various cartridges caliber 9.3mm to .510 and therefore I believe that I can differentiate a little what works well and what could possibly cause problems.

Nowadays we have so many good cartridges available for DG hunting so that we are not forced to fall back on cartridges like the 10,75x68 that were already replacement solutions in the past because nothing better was available or could be bought.