H4350 has been great in my 375s (3 of them). I just received 8lb of it.

475guy is right, to get the published max in the case (@81gr), you will need a drop-tube. BUT I've been able to reach acceptable velocities in my 375s with significantly less powder than the max load. So I say that you should definitely back off 10% of max load when working up a load.

My target velocit is about 2500-2540 fps (I personally don't see a need for extra wear & tear of the advertised 2650fps) and I'm able to reach my target velocities with 74-76gr of H4350 depending on the bullet used.

Overall, it gives good velocities at great pressures and it's about the slowest burning powder that you can get enough of into the case - vs the 4831s.