There are videos on youtube of that one being fired too-or at least, there were. Other than the sheer size it looks pretty tame-but with the weight of the thing you won't be firing it unsupported.

As for me shooting monsters like that I think I'm at my limit of handgun with my .45-70. It kills deer well but I'm done shooting after 5-10 rounds. It's the last gun that gets uncased on the range.