It'll work on BoBo, as well as everything else in N.A.
In my own .45x3-1/4", 2F was more accurate.
In your rifle, 62.0 gr. Re#7 + 300gr. Nosler will do wonders on everything here as well. That ran 2,200fps in my brother's Sharps & did well on a 2 yr. old bull moose. It would clover leaf at 100 meters for 3 shots using apertures. Needs a backer-rod filler.