Here's another off an Alaskan forum:

H4350 is ADI 2209.

"I have a .416 Ruger alaskan, and I use 73 grains H4350 with a Speer
350 grain Mag Tip. Also use this charge with a 350 gr. Kodiak.
I have yet to shoot anything alive with it, but penetration tests have been positive. I would not hesitate to use the Mag Tip on a Brownie.
The 350 gr. TSX also shoots well with this load.
This, and the .375 Ruger have proven to be untempermental and easy
to work with.
While the Houge stock shoots well from the bench, and does reduce
recoil, I added a Ruger synthetic from Brownells. It fit's my large hands better, and handles well.This is the same stock as the Compact Magnum comes with.