Are we talking hunting rounds, or stopping rounds - can be a huge difference. Seems most people think stoppers.
My favourite round isn't even on there - .376/06IMP.

My Mk10 Mauser chambered this ctg. carries 5 + one in the chamber and easily does over 2,450fps with 300's. It also does over 2,600fps with 270's - both exceed the published velocities of the original .375H&H made in 1912 and those ballistics which the .375 produced to develop it's reputation as a great ALL - ROUND HUNTING ctg. for the big 5.