Ok, here is my call:

17HMR for varmints
22 LR for the tiny stuff, plinking, and practice
7x57mm for general lightweight carry
7mm Remington Ultra Magnum Beanfield
350 African Express for the bigger stuff
416 Rigby for the big stuff
458 Win Mag for the big bore needs

Anything else is just stuff to own and keep in your safe....

RobertD