blackbearhunter,

I believe these heavy recoiling rifles do hurt the shoulder / rotator cuff muscle. Have a look
at a video in slow motion and you'll see what I mean.

I sometime get a sore neck.

Mostly shoot 465 / 470, 500 Jeffrey, 505 Gibbs, 500 Nitro in the bigger calibres.
I find alot of it has to do with how they are stocked / fit you.

500 Nitro