I would take the rifle I could shoot with the best accuracy under all shooting conditions - rest - various game positions and offhand - over all ranges I'd likely have to shoot.

I would choose either my .375/06IMP or my 9.3x62mm - not a .458 - probably the 9.3x62mm as it's handier with a 22" bl. and faster on target with it's 2X scope. Ballistically, they are identical - within 50fps.