In years gone by I loaded the 500 in the 460 at 2350. Plenty of speed, as much power as a 45 is gonna give you really, and "easy" shooting. The Lott and Express did the same thing in my guns.

Went with 600's due to customer demand. Had a year where all of them seemed to be hunting Elephant. Worked for me, as I sold all my bolt rifle stoppers....long story. Anyway we smuggled in a pile of Frontier CS and they worked great.

A 400 like a TSX or a Swift at 2400-ish would be a delight. Contact Hodgdon for data with there H4895, I seem to remember a reduced load with it and a 400