Due to a last minute .458 malfunction, I took my .375 H&H to Zimbabwe in May as my only rifle. I ended up shooting Cape Buffalo, Elephant, Hippo, and Lion with it as well as smaller game. In my opinion, if equally well hit, it kills as well as the .458 did. And it's a lot easier to shoot accurately.

It also seems to kick less than my .300 Weatherby with 180 grain bullets and, with 300 grain soft points, seems like it kills Impala and such a lot quicker. 3 shots on Impala and 3 DRTs.

I would not hesitate to take it as my only rifle on a DG hunt if I go in 2013, and probably will. I definitely don't think I'll be undergunned on elephant or buffalo.