Trex

If it was me, I would be taking my .375 M98 and my .450. Both will kill buff but the added ability of the .450 would be nice.

I wouldn't take a .338 and a .375. They are too close.

If I took one rifle, eg because of luggage weight, I would take just the.375 and did so on my last safari.

If I believed long shots were going to be necessary I would take the .300 unless I practiced a lot with the .375. I was handicapped with my .375 on my last trip when hunting bushbuck on irrigated cereal farms and animals were able to be sighted up to 800 metres away. This was unexpected. Some places it is to be expected.

So I guess I am also saying the .375 and the .458 Lott. Live the fantasy of Africa.

Have fun.