Well, I just got back from the range where I was playing with my brand new Ruger Hawkeye .416 with the overmold stock and stainless everything else.

Couple of points regarding loads.
1. Hornady makes a DG 400-gr. soft and solid.
2. Both shoot to the same point of aim at 50 yards.
3. The iron sights on the Ruger are set to 50 yards.
4. A Leupold VX-II 1-4x20 is awaiting installation.
5. 400-gr. at 2520 fps out of a 20 inch barrel is LOUD.
6. Kicks like a rabid mule; I don't care what other gun writers say. (Yup, I'm one - Dangerous Game Hunting Magazine, Small
Arms Review, and others)
7. I've taken up to Cape Buffalo with a .416. (Remington). Anyone who thinks he/she has a need for more zap out the loud end of
the barrel needs to be on the rubber end a few times. I've owned/shot up to a .Searcy .700 Nitro. My last Buf fell to a .458
Lott. I have faith that one of these days my shoulder will quit hurting, and the ugly red lines go away.
8. And lastly ... anyone who says you don't feel the recoil when you tap off a .400, or larger, caliber at an animal ... ummm,
dunno 'bout that. I'm good for 2-3 shots offhand these days; at the most, two from the bench, and hopefully only one when
hunting - they all hurt like hell.

I guess what I'm sayin' is go with the Hornady load, it will do anything anyone could want anywhere anytime on any animal.