I would have no problems with a Rem 700 on dangerous game. Yes I would probably put a Sako type extractor on it to grab more of the case. I have come across a few Mauser's and their clones that have minor and massive feeding and/or extraction problems and problems with bolts jamming while feeding and extracting. Sure they are not every day problems but nor are those that are experienced with Rem 700.

My 375H&H is a CZ550. each to his own