A much unsung advantage to the standard 375 H&H is that the tapered shoulder works well with light loads. I use it for rabbits! A 270 grain cast bullet at 1300 fps that is quite accurate, drills a neat hole and doesn't spoil the meat. The newer super duper blown out and improved sharp shouldered cases do not like such light loads.

Know think about this for a minute. If you are used to going out and getting rabbits with a 375, you'll probaby manage to hit that buffalo with it.