I have the 2.5 Leup on my 404, I love it, I shoot out to 150 with it when its on and that is all I will do with the 404.

Great scope on that gun. I agree with 4seventy re a 375 mag. The other question is what are you shooting it at and what kind of terrain do you shoot in? This will help you decide on your requirements.

Shooting at home or are you going to Africa with this gun?

I have a Zeiss 1.5x6 on my 300 and that is a great scope for what I use it for out to 300m on floodplain boars.

Just my two cents.....