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Would it be safe for the garden run human to add 2 lbs to Bigdog's range of weights?

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IMHO, Yes indeed.

My 450#2 weighs 11 1/4 and I enjoy shooting it. At 2 1/4 lbs less, I personally would dread taking it out of the cabinet. That would be less than my 9.3 x 62.

Regards