If and I say "if" I were going to get serious about such things I would want a quality mauser bolts,and a run a caliber spread like 300 H&H, 338 H&H(?ever created), 375H&H, 416 Rem, and 458Lott.

You could take the 338/416 combo on PG/DG hunts excluding Ele or a 375H&H/458 Lott combo on a multiple DG hunt from Lion to Hippo to Crocs to Buff to Ele ( I consider Croc and Hippo semi dangerous game).

You could carry a 300/375 combo for North American hunting!!

What combo's would work here??