Although I have enjoyed hunting with and shooting a couple Merkel 470NE's and a Kreighoff 9.3 and ALSO held a BLASER in 500NE and 375H&H.
I would and have considered a 450/400 in ether the German Heym or US made Searcy.
The 450/400 is a great option for a sport hunters Double rifle cartridge with less recoil than the 470NE and the ability to set it up with a quick release scope.

A Searcy Cassic 450/400