Impressive.

That combo(500gr @2450) obviously gives superb penetration.

If we play the SD game the 416 Weatherby solid looks good with a 450gr with a SD of .374.

Is this the best penetrating combo?

Methinks I would rather have a 510 diameter bullet(SD.318) with a 24% larger cross sectional area making the same hole and penetrating a bit less than the 416.The advantage of the cross sectional area of the 500NE is less vs a 458 diameter showing only a 11% increase in cross sectional area.A 500gr@ 2450 should penetrate further than any 500NE.

The bottom line is how much penetration is enough and not wasted?