I missed a frontal brain shot on a bull a couple years ago. He was charging and had dropped his head in the low position just the rifle went off and the shot was high. He whelled around and Hitailed it, but there was an askari bull with him that sided right up next to him so we could get a shot into the chest area. He was running away so tried to spine him, but missed it. My 2 PH's both fired also (I have standing orders with them than in this type of case they shoot to, I'm not going to leave an animal go or suffer longer because of pride) The bull tipped over in about 800 yds. 470 & 2-416's all with solids were used.