When hunting elephant last year the PH advised me to go for the brain shot with the first shot, but if it did not appear to hit the brain, not to try again and instead put a round into the heart/lungs.

I was using a .450 No. 2 Nitro Express double.

Obviously a good brain shot will drop the ele instantly. Even if only stunned but down, the second "insurance" shot into the chest makes sure it will still be there later on.

Obviously we are talking about an ele that isn't charging AFTER the first shot misses the brain. Maybe stopped, or wheeling to flee.

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Gentlemen,

What do you think? What have been your experiences?

Has anyone here tried for a brain shot, missed the brain, then tried again for the brain?