Allen, I gotta disagree here as I am fooling around with much the same idea in a 458WM. I'm using 400gr TBBC's, factory Federal ammo which actually have a higher BC and MV than a 400gr TBBC out of my 416 Rigby (again using Federal factory ammo) which makes the 458 a fine longer distance rifle for say, eland. I plan on using 500 gr African Grand Slams on the bigger stuff, so I am hoping to get to dead on at 50 yds with the AGS's and about three inches high at 50 yds with the TBBC's. This would give me a rifle that is within three inches of POA out to about 230yds and still have the better stopping power on buff. The 458 has more energy and a flatter trajectory than the 375H&H using 300 gr bullets when comparing the Federal factory loads. A rifle that shoots as flat as the 416's with a bit of added punch available short range is appealing to me.