Pretty sure no bowhunter steps up to a buffalo intending to aim for a specific artery.

Heart or double-lung is most often the intended outcome, on any mid- to large game. The quarry is never expected to drop to the shot!

...and I don't want the guy drawing 150lbs to be offering me a handshake!

Howard Hill's longbow for elephant was 125lbs draw-weight, and that was widely considered exceptional for the time.

Done a bit of bowhunting...