Part of your decision might be based on what part of Tanzania you will be hunting. I hear the Selous is pretty thick while the areas in Masai land and Kigosi are very open. I have been told that getting within 100 yards there can be difficult. I leave for Kigosi on Sept 15 for buffalo and hippo (and who knows what else will tickle my fancy). The outfitter and ph wanted me to bring my 375 HH, which I am bringing as the second gun, for the long shots. I want to hunt with my new 458 Lott. Will let you know about the conditions when I get back in October.

My guess now would be the Ackley 375 or the 416. Really, any of the 3 will work.