A 500 grain bullet doing above 2500 fps from a 458 lott would most likely be "devistating" for the shooter and also the rifle!

Every shooter is diffrent and every shooter has a diffrent level of what is unmanagable recoil, 2500fps is quite a snap for any rifle.
When I shoot my .458lott 500 grain @ 2350fps I can easily put round after round on target off the sticks or freehand. I think its more in the rifle you have built.
Mine is a bit hefty and custom built from the ground up for a heavy caliber, with that combo for all the jokes about the lott kicking your brains out the recoil is not very bad at all in the right rifle for someone farily recoil tolerant.

We will see when the .600OK comes in if this still holds true

IMO bigger is always better event when its not.

James F. Nixon III