We went hunting water buffalo with a mate carrying a 6.5x54 M-S.

People on here got upset, one even telephoned the outfitter and tried to stop the hunt .... btw NOT appreciated and none of their business! But all water under the bridge.

Anyway the 6.5x54 worked out with close in well aimed broadside shots.

My personal opinion is hunting buffalo with a 6.5 on foot probably wouldn't get you killed 19/20 times ...