I'm thinking I'll bring both guns, but I have six months to mull it over. In my 30-06 I currently shoot the Federal Premium 165 grain Trophy Bonded Bear Claw. It's an expensive load, but it shoots so very accurate, and when I last did ballistics on it - that bullet flew flatter and longer than a 180 or even a 220... who knows. Thus, my desire to bring the 375 for the bigger game. Oh well - either way, I'm pretty excited for the hunt!