big lizrds have small brains the size of of a good walnut so big does not matter why not a 308 a bullet in the brain will end all.yes you can use an RPG but why for surgical placement anyone of the 308's will do.but a hippo on land a nice double is what will make that dream a memory for life.and for buffalo you know what you are dreaming is a close encounter with a clasic double gripped between your seaty hands as your heart thumps out of your chest,tell me if i am wrong because i have the same dream and one day if god will grace me the chance thats what i want.its your dream what ever you decide will make you smile till thelast timeyou close your eyes.just do it.