Based on all of the good things I have read about the 9.3 x 62 I would choose that. But the others make a fine point. As long as the cost of ammo and being prepared are not issues I still like the 9.3. I would pass on the 338 and go for the 375 or 9.3 if Africa is in your future. That's Just my opinion. I think just as critical is the quality of the guns you might be able to buy. Nothing against those you listed but I think if you shopped a bit you could easily find a far nicer gun (used) for the $$$ in 375 H&H. I would not take the same gun to AK as Africa. One is pretty much a synthetic stock venture while the other begs for wood.