At the low velocity of 2,150fps to 2,300fps from a .358Win.(OR .356) the 250gr. Horandy RN's work just fine. mY Bro's .356 with 20" gets 2,150fps with the 250's and he uses it for his guide gun. So far, the 3 moose and black bears he's had to finish have all died rather abruptly. One of the moose was just over 200yards and the expansion was perfect on the quartering shot. Behind the last rib, ended up in the front of the off shoulder and the moose dropped at the shot.
: Where you place them counts.